Current Research Projects

Precision Assessments of Aging in the Individual

PI: Maxwell Elliott, Ph.D.

Representative Publications:

Elliott ML, Du J, Nielsen JA, Hanford LC, Kivisäkk P, Arnold SE, … & Buckner RL. Precision Estimates of Longitudinal Brain Aging Capture Unexpected Individual Differences in One Year (2025). Under Review. doi.org/10.1101/2025.02.21.25322553
Elliott ML, Nielsen JA, Hanford LC, Hamadeh A, Hilbert T, Kober T, … & Buckner RL. Precision brain morphometry using cluster scanning (2024). Imaging Neuroscience, 2. doi.org/10.1162/imag_a_00175
Elliott ML, Caspi A, Houts RM, Ambler A, Broadbent JM, Hancox RJ, … & Moffitt TE (2021). Disparities in the pace of biological aging among midlife adults of the same chronological age have implications for future frailty risk and policy. Nature Aging, 1(3), 295-308. doi.org/10.1038/s43587-021-00044-4

PI: Maxwell Elliott, Ph.D.

Representative Publications:

Whitman ET*, Elliott ML*, Knodt AR, Abraham WC, Anderson TJ, … & Hariri AR. An estimate of the longitudinal pace of aging from a single brain scan predicts dementia conversion, morbidity, and mortality (2025). Nature Aging. doi.org/10.1038/s43587-025-00897-z

PI: Maxwell Elliott, Ph.D.

Representative Publications:

Elliott ML (2020) MRI-based biomarkers of accelerated aging and dementia risk in midlife: How close are we? Ageing Research Reviews, 61. doi.org/10.1016/j.arr.2020.101075
Reuben A*, Elliott ML*, Abraham C, Broadbent J, Houts RM, Ireland D, … & Moffitt TE (2020). Association of childhood lead exposure with MRI measurements of structural brain integrity in midlife. JAMA, 324(19), 1970–1979. doi:10.1001/jama.2020.19998.
Elliott ML, Belsky DW, Knodt AR, Ireland D, Melzer TR, Poulton R, ... & Hariri AR (2019). Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth cohort. Molecular Psychiatry, 26, 3829-3838. doi.org/10.1038/s41380-019-0626-7
d’Arbeloff T.*, Elliott ML*, Knodt AR, Melzer TR, Keenan R, Ireland D, ... & Moffitt TE (2019). White matter hyperintensities are common in midlife and already associated with cognitive decline. Brain Communications, 1(1). doi.org/10.1093/braincomms/fcz041

PI: Maxwell Elliott, Ph.D.

Representative Publications:

Du J, Tripathi V, Elliott ML, Ladopoulou J, Eldaief MC & Buckner RL. Within-Individual Precision Mapping of Brain Networks Exclusively Using Task Data (2025). Neuron. doi.org/10.1016/j.neuron.2025.08.029
Elliott ML, Knodt AR & Hariri AR (2021). Striving toward translation: Strategies for reliable fMRI measurement. Trends in Cognitive Science, 25(9), 776–787. doi.org/10.1016/j.tics.2021.05.008
Elliott ML*, Knodt AR*, Ireland D, Morris ML, Poulton R, Ramrakha S, ... & Hariri AR (2020). What is the test-retest reliability of common task-fMRI measures? New empirical evidence and a meta-analysis. Psychological Science, 31(7), 792–806. doi.org/10.1177/0956797620916786
Elliott ML, Knodt AR, Kim MJ, Melzer TR, Keenan R, Ireland D, ... & Hariri AR (2019). General Functional Connectivity: shared features of resting-state and task fMRI drive reliable individual differences in functional brain networks. NeuroImage, 189, 516-532. doi.org/10.1016/j.neuroimage.2019.01.068